Effective reduction of primary dysmenorrheal symptoms through concurrent use of n-3 fatty acids and Rosa damascena extract (RDE)
Authors
Abstract:
Background: Primary dysmenorrhea (PD) is characterized by painful cramps of lower abdomen without abnormal pelvic pathology. PD begins some hours before or simultaneously with the onset of menstrual bleeding. Objectives: The purpose of this study was to investigate the effects of separate and concurrent supplementation of fish oils (FO) containing n-3 fatty acids and Rosa damascena Damascena extract (RDE) on PD symptoms. Methods: In this double blind clinical trial in 2015, through convenience sampling, 105 university students with primary menstrual pain in most recent years, without significant abnormal pathology, and with moderate/severe dysmenorrheadysmenorrheal symptoms according to visual analogue scale (VAS) were randomly assigned into one of four groups: 1. FO 1000 mg/day (n=26), 2. RDE 1000 mg/day (n=27), 3. FO and RDE concurrently, with the same dose (n=27), and 4. Control group (n=25). All measurements were performed three times, at the beginning, 30th day, and 60th day. Symptoms including nausea, vomiting, diarrhea, bloating, cramp, low back pain, headache, fatigue, anxiety, sweat, weakness, dizziness, drowsiness, and feeling cold were measured by VAS method. Results: After 2-month treatment, supplementation with RDE significantly reduced severity of bloating (p<0.001) and sweat (p<0.001), but FO supplementation had no significant effect on PD symptoms. The concurrent use of FO and RDE significantly decreased severity of diarrhea (p=0.038), weakness (p<0.001), dizziness (p=0.003), and feeling cold (p=0.049). Conclusion: Our results suggest that the concurrent supplementation of omega-3 fatty acids and RDE could be more effective than their separate use in decreasing PD symptoms; however, larger trials are warranted to confirm these preliminary findings.
similar resources
Cytobiochemical Potentials of Rosa damascena Mill. Extract
Background and Objectives: There is a profound inclination among people toward consumption of herbs and herbal products. Some of these products are harmful while health-promoting potentials of some others should be discovered. In the present study the antibacterial, antioxidant, acute and subchronic and cancer cell toxicity of methanolic and aqueous extracts of Rosa damascena Mill. was
full textPreventive use of N-3 fatty acids.
To the Editor: In the editorial “N-3 fatty acids: priority for post–myocardial infarction clinical trials,” Dr Scott Grundy1 (somewhat cautiously) endorsed the need for a trial to test the hypothesis that -3 fatty acid (FA) supplements will reduce risk for coronary death in patients randomized in the immediate post–myocardial infarction period. We support this recommendation, but we differ with...
full textEffect of Rosa damascena Mill. flower extract on rat ileum
Rosa damascena flower is widely used for gastrointestinal (GI) disorders. However, its pharmacological action on isolated ileum has not been studied. In this research, the effect of extract of flower petals of R. damascena Mill. growing in Kashan, Iran, on ileum motility was investigated. Hydroalcoholic extract was prepared by percolation method. A section of rat ileum was suspended in an organ...
full textThe Effect of Rosa Damascena Extract on Primary Dysmenorrhea: A Double-blind Cross-over Clinical Trial
BACKGROUND Dysmenorrhea is one of the most common types of cyclic pain that affects 50% of women and girls in their menstrual ages. Because of the side-effects and contraindications of chemical medicines, using herbs has been investigated in treating dysmenorrhea. OBJECTIVES The aim of this study was to determine the effect of Rosa damascena extract on primary dysmenorrhea among the students ...
full textPharmacological Effects of Rosa Damascena
Rosa damascena mill L., known as Gole Mohammadi in is one of the most important species of Rosaceae family flowers. R. damascena is an ornamental plant and beside perfuming effect, several pharmacological properties including anti-HIV, antibacterial, antioxidant, antitussive, hypnotic, antidiabetic, and relaxant effect on tracheal chains have been reported for this plant. This article is a comp...
full textmolecular and physiological characterizations of floral scent production in rosa damascena mill.
گل محمدی (r. damascena mill.)مهمترین گونه ای است که در تولید گلاب، عطر و اسانس، در صنعت عطرسازی و دارویی کاربرد دارد. با وجود اهمیت عطر گل محمدی، پژوهش های مولکولی و بیوشیمیایی عطر گل این گونه هنوز در مراحل ابتدایی است. در این پژوهش، ویژگی های مولکولی و فیزیولوژیکی تولید عطر در گل محمدی در آزمایش های مختلف مورد بررسی قرار گرفتند. در آزمایش اول، پژوهشی به منظور بررسی تنوع شیمیایی اسانس میان 44 ت...
My Resources
Journal title
volume 7 issue 2
pages 33- 40
publication date 2017-10
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023