Early Puberty Due to Ovarian Granulosa Tumor
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Abstract:
A 7½-year-old girl is reported showing precocious puberty and large abdominal mass for a year. The right ovarial cyst removed by surgery revealed histopathologically a granulosa cell tumor. After removal of the tumor the estrogens were still increased and the signs of puberty showed no regression. This seems to be due to the hormonal activity of the metastases. Liver metastasis was present at operation and the lumber vertebrale (L 1 -L:i) showed radiographic changes suggestive of osseous metastasis.
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Journal title
volume 2 issue 5
pages 363- 367
publication date 1974-08
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