Doppler echocardiographic findings in tissue engineered aortic valve in a sheep model

Tissue engineered aortic valve

Several prostheses are available to replace degenerative diseased aortic valves with unique advantages and disadvantages. Bioprotheses show excellent hemodynamic behavior and low risk of thromboembolic complications, but are limited by tissue deterioration. Mechanical heart valves have extended durability, but permanent anticoagulation is mandatory. Tissue engineering created a new generation h...

A tissue engineered heart valve implanted in a juvenile sheep model.

BACKGROUND The tissue-engineered (TE) heart valve was developed to improve the durability of tissue heart valves. The aim of this study was to evaluate morphological and histological changes in a TE heart valve consisting of decellularized porcine matrices seeded with viable autologous vascular endothelial cells (AVEC). MATERIAL/METHODS TE valves were implanted into the right ventricular outf...

Incidental echocardiographic findings of a quadricuspid aortic valve associated with aortic regurgitation in a cat

CASE SUMMARY A 10-month-old male domestic shorthair cat was brought to Kitanomori Animal Hospital for routine castration. Preoperative thoracic radiography revealed a mildly enlarged heart silhouette, and transthoracic echocardiography (ECHO) suggested a quadricuspid aortic valve associated with central aortic regurgitation (regurgitant fraction 31%). After sedation with intramuscular medetomid...

Aortic valve allografts in sheep.

Some of the mechanical and biological problems surrounding the use of fresh allograft inverted aortic valves as mitral valve substitutes are described. Certain aspects of the problem have been studied expzrimentally. In three sheep 'fresh' aortic valve allografts were-inserted, using cardio-pulmonary bypass, into the main pulmonary artery, and were observed from 5 to 7 months after operation. T...

Ross procedure with a tissue-engineered heart valve in complex congenital aortic valve disease.

M-mode, Two-dimensional, Spectral Doppler and Tissue Doppler Echocardiographic Findings in 40 Healthy Pet Rabbits

Next to dogs and cats, rabbits are popular companion animals in the United Kingdom with 1.7 million kept as pets. Almost 60% of these rabbits are registered with a veterinary practice. The number of reported or anecdotal reports describing congenital or acquired cardiac diseases is increasing, which results in a growing demand to perform echocardiography in pet rabbits as clinical cases. Report...