Detection of Anti-Ganglioside Antibodies in Guillain-Barre Syndrome

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Detection of anti-ganglioside antibodies in Guillain-Barre syndrome.

Sera from 40 patients with Guillain-Barré syndrome (GBS), including the subtypes acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor and sensory axonal neuropathy (AMSAN), and Miller Fisher syndrome (MFS) were examined for the presence of anti-ganglioside antibodies using the ganglioside agglutination assay, and the enzyme-linked immunosorbe...

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Comparison of Immunoblotting and ELISA for Detection of Anti-Ganglioside Antibodies in Children with Guillain-Barre Syndrome

Background: Anti-ganglioside antibody assays are widely used for diagnosis of autoimmune peripheral neuropathies. Objective: This study aimed to determine serum levels of anti-ganglioside antibodies in children with Guillain-Barre syndrome by immunoblotting technique and compare the results with those obtained by ELISA method. Method: In this investigation, 50 children with Guillain-Barre syndr...

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comparison of immunoblotting and elisa for detection of anti-ganglioside antibodies in children with guillain-barre syndrome

background: anti-ganglioside antibody assays are widely used for diagnosis of autoimmune peripheral neuropathies. objective: this study aimed to determine serum levels of anti-ganglioside antibodies in children with guillain-barre syndrome by immunoblotting technique and compare the results with those obtained by elisa method. method: in this investigation, 50 children with guillain-barre syndr...

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Comparison of immunoblotting and ELISA for detection of anti-ganglioside antibodies in children with Guillain-Barre syndrome.

BACKGROUND Anti-ganglioside antibody assays are widely used for diagnosis of autoimmune peripheral neuropathies. OBJECTIVE This study aimed to determine serum levels of anti-ganglioside antibodies in children with Guillain-Barre syndrome by immunoblotting technique and compare the results with those obtained by ELISA method. METHOD In this investigation, 50 children with Guillain-Barre synd...

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Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse

Objectives: Anti-ganglioside antibodies are present in about half of the patients with Guillain-Barré syndrome (GBS). Recently it has been shown that a considerable proportion of these patients has serum antibodies against antigenic epitopes formed by a complex of two different gangliosides. However, direct experimental evidence for neuropathogenicity of this special category of antibodies is c...

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Journal title

volume 7  issue 3

pages  198- 201

publication date 2010-09-01

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