Complex Arterial and Venous Thrombosis in Polycythemia Vera: what Does Leukocytosis Predict?

Authors

  • Denny Suwanto Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Eka Prasetya Budi Mulia Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Muhammad Aminuddin Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Hospital, Surabaya, Indonesia
Abstract:

Thromboembolic events represent the main cause of morbidity and mortality in patients with polycythemia vera. Leukocytosis has been identified as an important risk factor for development of vascular thrombosis. A 47-year-old woman with polycythemia vera presented with pain and swelling in her right calf. She was scheduled to receive anagrelide which was effective on polycythemia and thrombocytosis, but leukocytosis persisted. She was diagnosed with thrombosis in right popliteal vein and left common femoral vein by duplex ultrasonography. We suggested a role for leukocytosis in inducing thrombotic phenomenon in our patient with polycythemia vera.

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Journal title

volume 14  issue 1

pages  33- 36

publication date 2022-03

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