Comparison of Bladder Dysfunction and Urinary Symptoms Between Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
Authors
Abstract:
Background: Neuromyelitis optica (NMO) and multiple sclerosis (MS) are auto immune demyelinating disorders. Both MS and NMO patients suffer from urinary dysfunction. Objectives: Investigation of frequency and severity of urinary symptoms in two groups of MS and NMO patients. Materials & Methods: 56 MS patients and 20 NMO patients were enrolled in this cross sectional study conducted in Isfahan Kashani hospital from March 2018 to September 2018. Frequency and severity of urinary symptoms were assessed using the urogenital distress inventory (UDI-6) and international prostate symptom score (IPSS) questionnaire. Data were analyzed using independent t-test, Mann Whitney U test and Pearson correlation coefficient with the SPSS V. 18. Results: The Mean±SD of age was 40.2±11.45 and 34.1±9.09 in NMO and MS group respectively. There was a significant difference between MS and NMO patients regarding their overall IPSS score (9.8±7.9 and 14.6±11.3 respectively). The frequency of mild, moderate and severe urinary symptoms was 25%, 50 % and 25% among NMO patients and 48.2%, 35.7% and 16.1% among MS patients respectively. Based on UDI-6 questionnaire the most frequent symptoms in MS and NMO patients were frequency and urgency respectively and they are more frequent among NMO patients rather than MS patients. Conclusion: Our results showed a significant difference in frequency and severity of urinary symptoms between NMO and MS patients and NMO patients tend to experience more severe urinary symptoms.
similar resources
Comparison of cognitive and brain grey matter volume profiles between multiple sclerosis and neuromyelitis optica spectrum disorder
OBJECTIVE Brain regions responsible for cognitive dysfunction in MS and neuromyelitis optica spectrum disorder (NMOSD) are not known. Our aim of this study was to investigate whether cognitive function and brain volume differed between MS and NMOSD in Japanese patients. METHODS Brain MRI and neuropsychological tests including the Wechsler Adult Intelligence Scale-III (WAIS-III), Wechsler Memo...
full textA Urinary Metabolic Signature for Multiple Sclerosis and Neuromyelitis Optica.
Urine is a metabolite-rich biofluid that reflects the body's effort to maintain chemical and osmotic homeostasis. Clinical diagnosis routinely relies on urine samples because the collection process is easy and noninvasive. Despite these advantages, urine is an under-investigated source of biomarkers for multiple sclerosis (MS). Nuclear magnetic resonance spectroscopy (NMR) has become a common a...
full textAssociation Between Helicobacter Pylori Infection and Seronegative Neuromyelitis Optica Spectrum Disorder
Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease in the central nervous system. Association between NMOSD and Helicobacter pylori (H. pylori) infection has been investigated, but few studies have assessed the relationship between H. pylori and seronegative AQP4-Ab NMOSD. Objectives: This study aimed to survey the association between H. pylori...
full textOptical Coherence Tomography and Magnetic Resonance Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
Irreversible disability in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) is largely attributed to neuronal and axonal degeneration, which, along with inflammation, is one of the major pathological hallmarks of these diseases. Optical coherence tomography (OCT) is a non-invasive imaging tool that has been used in MS, NMOSD, and other diseases to quantify damage to th...
full textComparison between the cranial magnetic resonance imaging features of neuromyelitis optica spectrum disorder versus multiple sclerosis in Taiwanese patients
BACKGROUND Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) are inflammatory diseases of the central nervous system with different pathogenesis, brain lesion patterns, and treatment strategies. However, it is still difficult to distinguish these two disease entities by neuroimaging studies. Herein, we attempt to differentiate NMOSD from MS by comparing brain lesion pat...
full textMetabolomic profiling of CSF in multiple sclerosis and neuromyelitis optica spectrum disorder by nuclear magnetic resonance
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory diseases of the central nervous system. Although several studies have characterized the metabolome in the cerebrospinal fluid (CSF) from MS and NMOSD patients, comparative analyses between them and between the relapse and the remission of each disease have not been performed. Both univariate and multivar...
full textMy Resources
Journal title
volume 5 issue 3
pages 105- 110
publication date 2019-08
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023