Comparative Effectiveness of Antidepressant Medication versus Psychological Intervention on Depression Symptoms in Women with Infertility and Sexual Dysfunction

Authors

  • Farzan Kheirkhah Departments of Psychiatry, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
  • Mahbobeh Faramarzi Social Determinants of Health Research Center, Babol university of Medical Sciences,Babol, Iran.
  • Zahra Basirat Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Abstract:

Objective Loss of fertility is a challenging experience. The present study was conducted to compare the effectiveness antidepressant medication versus psychological treatment of depressive symptoms in infertile women suffering sexual dysfunction (SD). MaterialsAndMethods A randomized controlled clinical trial was completed from December 2014 to June 2015 in Babol, Iran. Of the 485 participants, 93 patients were randomly assigned in a 1:1:1 ratio to psychosexual therapy (PST), bupropion extended-released 150 mg per day (BUP ER), and control (no intervention) groups. The Beck depression inventory (BDI) was completed at baseline and end of study (After eight weeks). Statistical analyses were done using paired-test and Analysis of covariance. Results The mean BDI score of participants was 22.35 ± 8.70 at baseline. Mean BDI score decreased significantly in each treatment group (PST: P

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Journal title

volume 12  issue 1

pages  6- 12

publication date 2018-06-01

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