Combination antifungal therapy without craniotomy in an immunocompromised patient with rhino-orbito-cerebral mucormycosis: A case report
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Rhino-orbito-cerebral mucormycosis.
A 12-year-old female patient started with sudden abdominal pain, polyuria, polydipsia, anorexia and a drop in conscience level. She was diagnosed with untreated type I diabetes mellitus (diabetic acidosis), with blood sugar of 508 mg/dl upon hospital admission. After one week in the hospital, she started having eyelid ptosis, facial pain, converging strabismus, left side epistaxis and a progres...
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A case of rhino-orbito-cerebral mucormycosis is presented showing its aggressive nature and progression of disease. The typical clinical features, neuroimaging and histological findings are highlighted in this report. Amphotericin B and surgical debridement remain the mainstay of treatment. However, associated co-morbidities need to be addressed.
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Rhino-orbito-cerebral mucormycosis is an uncommon aggressive life-threatening opportunistic fungal infection that affects mainly the immunocompromised population with mortality rate up to 50%. Due to its aggressive nature, early detection and prompt management are of great importance for a good prognosis. Our report describes a fatal outcome of a case of rhino-orbito-cerebral mucormycosis follo...
full textRhino-Orbito-Cerebral Mucormycosis: A Case Report and Review of the Literature
Rhino-orbito-cerebral mucormycosis is a rare, opportunistic and often fatal fungal infection usually occurring in immuno-compromised or diabetic patients. The treatment involves administration of Amphotericin B and surgical debridement. Due to its lethal nature, early recognition of the infection is essential. This paper reports a case of rhino-orbito-cerebral mucormycosis, which developed in a...
full textcombination antifungal treatment for sino-orbito-cerebral mucormycosis: a case report
introduction invasive mucormycosis is an opportunistic fungal infection in patients with predisposing factors. case presentation we report a case of sino-orbito-cerebral mucormycosis in a diabetic patient successfully treated with combination of liposomal amphotericin b (l-amb) and posaconazole. conclusions clinicians should be alert of the clinical presentation of this fulminant fungal infecti...
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Journal title
volume 11 issue 2
pages 16- 0
publication date 2020-03
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