Clean synthesis of 1,8-dioxo-octahydroxanthene derivatives using NBS as an efficient and almost neutral catalyst in aqueous media

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Abstract:

An efficient one-pot condensation for the synthesis of 1,8-dioxo-octahydroxanthene is  achieved through a condensation of aryl aldehydes and 5,5-dimethyl-1,3-cyclohexandione in the presence of  NBS. This method enjoys several advantages such as low cost, simple work up procedure and safe reaction condition. In addition, water was chosen as a green solvent.

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Journal title

volume 1  issue 1

pages  11- 17

publication date 2008-10-20

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