Case series of rhinocerebral mucormycosis occurring in diabetic patients

Authors

  • Bijan Iraj Department of Endocrinology, Isfahan University of Medical Sciences, Isfahan, Iran
  • Kamyar Mostafavizadeh Department of Infectious Diseases, Al-Zahra hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mohammad Amin Sayedain Department of Cardiology, Chamran Hospital (Heart Centre), Isfahan University of Medical Sciences, Isfahan, Iran
  • Mohsen Meidani Department of Infectious Diseases, Al-Zahra hospital, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mojgan Mokhtari Department of Pathology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  • Pooria Hamedani Department of Endocrinology, Isfahan University of Medical Sciences, Isfahan, Iran
  • Rasoul Mohammadi Department of Medical Parasitology and Mycology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:

 Background: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%).  Case Presentation: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database.  Conclusion: In patients with mucormeosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.  

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Case series of rhinocerebral mucormycosis occurring in diabetic patients

BACKGROUND Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). CASE PRESENTATION In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients we...

full text

case series of rhinocerebral mucormycosis occurring in diabetic patients

background: rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. in most cases, infection is caused by inhalation of fungal spores. mortality rate of patients is very high (40-85%).  case presentation: in this study, three diabetic patients with rhinocerebral mucormycosis were presented. the etiologic agents of mucormycosis in two patients w...

full text

Rhinocerebral Mucormycosis: Report of a Rare Case

BACKGROUND Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying...

full text

Rhinocerebral mucormycosis: an update.

BACKGROUND AND OBJECTIVES Mucormycoses are a group of invasive infections caused by filamentous fungi of the Mucoraceae family, with the rhinocerebral form of the disease being the most common in large case series. In the present paper we review the characteristics of the rhinocerebral form of the disease. EVIDENCE AND INFORMATION SOURCES The present review is based on the analysis of the cur...

full text

Perineural spread of rhinocerebral mucormycosis.

An unusual pathway of local spread of rhinocerebral mucormycosis is presented with MR and pathologic correlation. Perineural extension, proved with pathology, followed the trigeminal nerve to the pons. Enhancement of the nerve was seen on MR.

full text

Two Cases of Rhinocerebral Mucormycosis

Mucormycosis is a rare opportunistic fungal infection. The most common infection site is the paranasal sinuses, although it can also occur in the lungs and skin. The fungus adheres to tissue membranes and forms thrombi, causing ischemia and hemorrhagic necrosis. Rhinocerebralmucormycosiscan occurin the nose, but mightrapidly spread to the orbit and intracranium. Therefore, prompt and aggressive...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 6  issue None

pages  243- 246

publication date 2015-10

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023