Carotid Body Paraganglioma with Prominent Lymphocytic Infiltration Mimicking Metastatic Lymph Node: A Case Report

Authors

  • Elham Jafari Department of Pathology, Afzalipour Kerman University of Medical Sciences, Kerman, Iran
  • Foroogh Mangeli Department of Pathology, Shahid Beheshti University of Medical Science, Tehran, Iran
  • hamid tabrizchi Department of Pathology, Kerman University of Medical Sciences, Kerman, Iran
Abstract:

Carotid body paraganglioma is a neuroendocrine neoplasm of the mandibular region. Due to its prominent stromal alternations, carotid body paraganglioma is a great emulator of other neoplasms in the head and neck region especially in metastatic tumors and its definite diagnosis is a great challenge. To the best of our knowledge, the most frequently reported variant is sclerosing and paraganglioma with a prominent lymphoplasmacytic infiltration is extremely rare. We report a rare case of a carotid body lymphoplasmacytic paraganglioma presented as a single asymptomatic mass of the right mandibular region in a 45-year-old woman. In order to exclude other possibilities, the use of immunohistochemistry is essential which shows a strong positive immunoreaction for chromogranin and synaptophysin. Surgical resection is the treatment of choice which is replaced with radiotherapy in contraindications. Overall, the tumor has a favorable clinical outcome.

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Journal title

volume 15  issue 1

pages  52- 55

publication date 2020-01-01

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