ASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN

Authors

  • H HOSSEINI
  • KM ADIB From the Immunogenetic Laboratory of Aliasghar Hospital, Isfahan University of Medical Sciences,
Abstract:

Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

association of hla-b27 with ankylosing spondylitis in isfahan, iran

using a standard microcytotoxicity (nih) technique of tissue typing, the hla-b27 antigen was identified in 30 out of 34 patients (hh.2%) with classical ankylosing spondylitis (as), compared to 6 out of 70 controls (h.6%) (p < 0.005). we also found this antigen in 8 out of 76 (10.5%) patients with non-as arthritis.

full text

HLA-B27 and Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory disease with potential disabling outcomes. Clinically, patients presented with inflammatory lower back pain, enthesis and alternated buttock pain (van der Linden & van der Heijde, 1998). Bernard Corner (16661698) was the first physician who published the clinical features of AS in his medical thesis (Baker & Weisman, 2006). In the late 19th ...

full text

HLA B27 and risk of ankylosing spondylitis.

'Noble, W C, and Naidoo, J, British Journal of Dermatology, 1978, 98, 481. 2 Porthouse, A, et al, Lancet, 1976, 1, 20. 3Ayliffe, G A J, et al, Journal of Clinical Pathology, 1977, 30, 40. 4Lacey, R W, Journal of Medical Microbiology, 1971, 4, 73. 5 Selwyn, S, and Chalmers, D, British J3ournal of Dermatology, 1965, 77, 349. 6 British Medical3Journal, 1978, 1, 1573. 7British Medical3Journal, 1977...

full text

Prevalence of HLA-B27 and subtypes of HLA-B27 associated with ankylosing spondylitis in Galicia, Spain.

OBJECTIVE To assess the prevalence of HLA-B27 and its subtypes in both the normal population and in patients with Ankylosing Spondylitis (AS) in Galicia, Northwest Spain. METHODS The prevalence of HLA-B27 in the normal population was determined by checking the number of HLA-B27 positive samples in 308 subjects from different areas of Galicia who had donated organs over a period of 4 years. A ...

full text

extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis

Objective-To investigate the potential influence of the HLA-linked LMP2 gene on disease susceptibility in HLA-B27 individuals with ankylosing spondylitis (AS). Methods-A polymorphic CfoI restriction enzyme site in the coding region of the LMP2 gene was evaluated in genomic DNA samples from 193 white and 49 Chinese B27 individuals with well documented AS, 97 of whom had had acute anterior uveiti...

full text

Association of HLA-B27 status and gender with sacroiliitis in patients with ankylosing spondylitis

OBJECTIVE To observe the influence of human leucocyte antigen B27 (HLA-B27) status and gender on sacroiliitis on computed tomography (CT) in ankylosingspondylitis (AS). METHODS We reviewed the archived medical records of the AS inpatients admitted in the Rheumatology Department of the First Affiliated Hospital of Wenzhou Medical University during the period from January 2007 through January 2...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 8  issue 3

pages  159- 161

publication date 1994-11

{@ msg @}

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023