Association between CYP19A <G rs700518 Polymorphism with Acne Vulgaris and its Severity: Influence on Sex Hormones Level

Authors

  • Ali Ebrahimi Department of Dermatology, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Asad Vaisi-Raygani Fertility and Infertility Research Center, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Ebrahim Shakiba Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Fariborz Bahrehmand
  • Mehrangiz Shafie Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Mona Akbari Department of Dermatology, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Rozita Naseri Department of Internal Medicine, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Ziba Rahimi Department of Dermatology, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Zohreh Rahimi Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Zomorod Ghadami Department of Dermatology, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Abstract:

Acne vulgaris (AV) is a common skin disease that causes physical and psychological problems for affected individual. In addition to systemic changes in hormone levels, overproduction of local steroids, especially androgens are associated with AV. Cytochrome (CYP) 19 is involved in the synthesis of estrogens. The aim of the present study was to investigate the influence of CYP19A

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volume 8  issue 2

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publication date 2019-07

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