Assessment of Ultrasound / Radio-guided Occult Lesion Localization in Non-palpable Breast Lesions
Authors
Abstract:
Objective(s): Controversy exists about the localization of non-palpable breast lesions. In many countries, the gold standard for the diagnosis of these lesions is needle localization due to its accuracy. This study sought to compare the ultrasoundand radio-guided occult lesion localization (ROLL) as a simple method with the conventional procedures in terms of their diagnostic power. Methods: This study was conducted on 94 patients with non-palpable breast lesions detected by ultrasonography and localized by the combination of ultrasonography and using radiopharmaceuticals. One to ten hours prior to surgery, 0.1-0.2 ml (equivalent to 0.5-1 mCi) of Tc-99m-phytate was injected to the lesion under the guidance of ultrasonography. Then, the lesion was localized using a hand-held gamma probe, and excision of the lesion was performed according to its radioactivity signal. Data analysis was performed using SPSS, version 16. Results: Benign and malignant pathologic results were observed in 77 (81.9%) and 17(18.1%) of the patients, respectively, and the mean volume of the excised tissue was 26.29±27 mm³. 79 patients had a solitary lesion (84%), 55 in the left breast (58.5%) and 39 in superolateral quadrant (41.5%). The mean size of the lesions was 15.7 mm in diameter (ranging from 4 to 34 mm). Additionally, there was a need to secondary surgery in 3 (3.2%) patients and inappropriate localization in 6 (6.4%) patients (subcutaneous or intra-ductal spread of radiodrug). Conclusion: Combination of ultrasound- and radio-guided localization methods for localizing non-palpable breast lesions is a simple and acceptable method for localization with no significant complications. For radio-drug spread and subsequent excessive excised tissue volume, subcutaneous and intra-ductal lesions are not suitable indication for ROLL.
similar resources
assessment of radio-guided occult lesion localization associated with sonography in nonpalpable breast lesions
conclusions radio-guided localization of non-palpable breast lesions is an acceptable method because of technical facilitation, accurate localization and complete excision with limited complications. so it can be recommended as an alternative method for wire-guided localization. results pathologic results were benign in 90.5% and malignant in 9.5% of patients. post-operative margin of lesion wa...
full textRadioguided occult lesion localization versus wire-guided localization for non-palpable breast lesions: randomized controlled trial
AIM This prospective randomized clinical study was conducted to compare radioguided occult lesion localization (ROLL) with wire-guided localization to evaluate optimum localization techniques for non-palpable breast lesions. METHODS A total of 108 patients who were undergoing an excisional biopsy for non-palpable breast lesions requiring pathologic diagnosis were randomly assigned to the ROLL...
full textApplicability of Radioguided Occult Lesion Localization in Non-Palpable Benign Breast Lesions
Mammography screening programs are frequently used for the detection of non-palpable clinically occult breast lesions and the widespread use of high-resolution ultrasound has increased the number of detected masses. Although most of the detected masses are benign and do not require surgery, sometimes surgery is needed because of discordance between results of pathologic and radiologic examinati...
full textRadio-guided occult lesion localization for nonpalpable suspicious breast lesions: A novel technique
Background: Breast screening programs and increased self-awareness has led to increased identification of early breast cancers. Up to 25% of mammographicaly identified lesions are nonpalpable, which require a precise technique to localize and excise completely. Radio-guided occult lesion localization (ROLL) is a technique, which uses hand held gamma probe to accurately localize and completely e...
full textNeedle localization of non-palpable breast lesions.
Screening mammography identifies suspicious, non palpable mammary lesions. Mammographic needle localization (MNL) is currently being used to facilitate excision biopsy of these lesions. Thirty-two patients underwent biopsies of the breast after MNL for non-palpable lesions. Mammographic indications for biopsy consisted of microcalcifications (48%), mass or abnormal density (21%) or mass+abnorma...
full textMy Resources
Journal title
volume 6 issue 1
pages 10- 14
publication date 2018-01-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023