Antiplasmodial ativity of akaloids from Garcinia Parvifolia Miq. Stem Bark

Authors

  • H. Sudrajat Ikatan Mahasiswa Eksakta Indonesia, Barek, Sleman 55281, Yogyakarta, Indonesia
  • R.A. Rahima Advance Medical & Dental Institute, Suite 121, EUREKA Complex,Universiti Sains Malaysia, Minden 11800, Penang, Malaysia
  • S. Khairi Ikatan Mahasiswa Eksakta Indonesia, Barek, Sleman 55281, Yogyakarta, Indonesia
  • U.Z. Lathifah Advance Medical & Dental Institute, Suite 121, EUREKA Complex,Universiti Sains Malaysia, Minden 11800, Penang, Malaysia
Abstract:

Garciniavalline (1), a novel aporphinoid alkaloid, in addition to four known alkaloids,cleistopholine (2), O-methylmoschatoline (3), (-)-oliveroline (4) and (-)-oliveridine (5), wereisolated and characterized from Garcinia Parvifolia Miq. stem bark. Structural elucidation ofthese compounds was established by spectroscopic methods. Among them, alkaloids (2) and (4)exhibited antiplasmodial activity against Plasmodium falciparum

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Journal title

volume 3  issue 1

pages  59- 63

publication date 2010-12-31

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