Antibacterial Activity of Germicide-P : A Persulfate Based Detergent/Disinfectant on Some Hospital Isolates
Authors
Abstract:
A novel chemical detergent/disinfectant formulated based on persulfate salts, germicide P , is available for disinfection of surfaces and medical devices at the room temperature. Because of the resistance of hospital-resident microorganisms, the antimicrobial activity of this compound is evaluated in the present study. The tests conducted with this disinfectant included bactericidal tests against 25 clinical isolates of gram negative bacteria of Escherichia coli, Pseudomonas aeruginosa as well as 25 clinical isolates of gram positive bacteria of Staphylococcus aureus with and without 5% bovine serum albumin (BSA) as dirty condition. All of the experiments also performed using standard strains and serial dilution method applied to find minimum bactericidal concentration (MBC) of germicide P against the selected bacteria at different exposure times. Also, to determine the ability of germicide P for disinfection of surfaces, standard surface tests were conducted using all of the clinical isolates as well as standard strains. According to the in vitro results of the tests, germicide P found to be a promising product with the MBC of 1/10 after 5 min. against all of the tested bacteria at the room temperature, however, the results of the surface tests indicated that a significant reduction in the efficacy of germicide P was observed and the MBC dropped to 1/5. In conclusion, surface antisepsis without intervention of organic materials in the concentration range of 1/5 was achieved with this new disinfectant.
similar resources
antibacterial activity of germicide-p : a persulfate based detergent/disinfectant on some hospital isolates
a novel chemical detergent/disinfectant formulated based on persulfate salts, germicide p , is available for disinfection of surfaces and medical devices at the room temperature. because of the resistance of hospital-resident microorganisms, the antimicrobial activity of this compound is evaluated in the present study. the tests conducted with this disinfectant included bactericidal tests again...
full textAntibacterial Activity and Phytochemical Screening of Acalypha wilkesiana (Copperleaf) Leaf Extract on Some Clinical Isolates
Ethanolic extract of fresh leaves of Acalypha wilkesiana was screened for its phytochemical and invitro antibacterial properties on four clinical isolates Staphylococcus aureus, Escherichia coli , Shigella sp , and Klebsiella pneumonia. The disc diffusion technique was used to assay for the antimicrobial properties. The results showed that the extract of concentrations between 50mg/ml to 200mg/...
full textThe antibacterial activity of some essential oils against clinical isolates of Acinetobacter baumannii
Acinetobacter baumannii is categorized as a red alert pathogen that is increasingly associated with a high mortality rate in infected patients due to its resistance to extensive antibiotics. In this study, we evaluated the antibacterial activities of some essential oils (Oliveria decumbens, Pelargonium graveolens, Eugenia caryophyllata, Ziziphora tenuir and Trachyspermum copticum oils) against ...
full textIn vitro antibacterial activity of piperacillin versus piperacillin- tazobactam on gram negative clinical isolates from a tertiary care hospital
Title: In vitro antibacterial activity of piperacillin versus piperacillintazobactam on gram negative clinical isolates from a tertiary care hospital.Objective :To compare in-vitro antibacterial activity of piperacillin with piperacillin-tazobactam combination on the most common isolates of gram negative bacilli obtained from various clinical samples from a tertiary care hospital. Methodology :...
full textAntibacterial Activity of Some Plant Extracts Against Extended- Spectrum Beta-Lactamase Producing Escherichia coli Isolates
BACKGROUND The extended-spectrum beta-lactamase (ESBL) -producing Escherichia coli isolates make many serious infections, especially urinary tract infections. OBJECTIVES The purpose of this study was to determine the antibacterial activities of some natural plant extracts against ESBL-producing E. coli isolates, which harbor the TEM gene in urine samples of the patients who have urinary tract...
full textMy Resources
Journal title
volume 2 issue 4
pages 225- 230
publication date 2006-10-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023