Anti-Trichomonas Vaginalis Activity of Ethanolic Extracts of Medicago Sativa and Satureja Hortensis, In Vitro Study

Authors

  • Aref Teimouri Department of Medical Parasitology and Mycology, School of Public Health, Tehran university of Medical Sciences, Tehran, Iran
  • Bahman Rahimi Esboei Department of Medical Parasitology and Mycology, School of Public Health, Tehran university of Medical Sciences, Tehran, Iran.
  • Farzaneh Mirzaei Department of Parasitology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
  • Fateme zare Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Mahdi Dehghan-manshadi Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Mohammad Ali Mohaghegh Department of Laboratory Sciences, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
  • Parisa Mousavi Department of Medical Parasitology and Mycology, School of Public Health, Tehran university of Medical Sciences, Tehran, Iran
  • Vahid Raissi Department of Medical Parasitology and Mycology, School of Public Health, Tehran university of Medical Sciences, Tehran, Iran
Abstract:

Background and Aims: Trichomonas vaginalis is a flagellated protozoa that is associated with vaginitis, cervicitis, urethritis and other vaginal disorders. Current study aimed to evaluate the anti-Trichomonas activity of Medicago sativa and Satureja hortensis, in vitro. Materials and Methods: Ethanolic extract of Medicago sativa and Satureja hortensis were obtained by rotary evaporator. anti-Trichomonas vaginalis activities of the extracts in different concentrations were evaluated after 24, 48 and 72 hr of incubation of the cultured media. Results and Conclusions: The data showed a significant difference between concentration and time regarding the Satureja hortensis and Medicago sativa extracts compared to the negative control (p<0.05). According to the results, the anti- trichomonas activity of the Medicago sativa and Satureja hortensis extracts may make it possible to use them in the treatment of trichomoniasis.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

In-vitro Activity of Ferula gummosa Essential Oil and Its Different Extracts on Trichomonas vaginalis

Introduction: Trichomonas vaginalis infection is one of the most common sexually transmitted diseases worldwide. Moreover, there are reports indicating the increasing rate of refractory trichomoniasis. The aim of this study was to evaluate the efficacy of Ferula gummosa on T. vaginalis. To this end, the chemical compositions of Ferula gummosa essential oil were identified in this study.    Mat...

full text

Anticonvulsant effect of Satureja hortensis aerial parts extracts in mice

OBJECTIVE Regarding the anticonvulsant effects of Satureja hortensis (S . hortensis) in Avicenna's book: canon of medicine; the present study was undertaken to evaluate the anti- eplileptic effects of S . hortensis aqueous and ethanolic aerial part extracts. Furthermore, the mechanisms of their anticonvulsant activities were also evaluated. MATERIALS AND METHODS Seizure was induced by Pentyle...

full text

Antioxidant Activity of Methanol and Ethanol Extracts of Satureja hortensis L. in Soybean Oil

Background: Considering the wide consumption of some synthetic antioxidants and their probable negative health effects, in this study, the protective effects of Satureja hortensis L. extracts in stabilizing soybean oil against oxidation at different concentrations (200 and 400 ppm) were tested. Methods: The aerial parts of S. hortensis L. were collected from Isfahan province and extracted with...

full text

Therapeutic effects of Iranian herbal extracts against Trichomonas vaginalis

Trichomonas vaginalis is a flagellated parasite affecting about 276 million people annually worldwide. Tricomoniasis is associated with different complications in pregnant women and infants. 5'-nitroimidazole derivatives (metronidazole, ornidazole, and tinidazole) are FDA approved drugs recommended for trichomoniasis treatment. Treatment with metronidazole 5'-nitroimidazole derivatives is assoc...

full text

In vitro activity of Arbutus unedo leaf extracts against Trichomonas vaginalis trophozoites.

Trichomonas vaginalis (T. vaginalis) is a flagellated protozoan commonly causing sexually transmitted disease. T. vaginalis infections are treated with a 5-nitroimidazole derivate. However, drug resistance has been known to occur for a long time and new alternatives are under investigation. Arbutus unedo is a wild plant mainly growing in maquis and rocky places of the seaboard in Southern Europ...

full text

Spermicidal and anti-Trichomonas vaginalis activity of Brazilian Sapindus saponaria

BACKGROUND Sapindus saponaria is used traditionally for curing ulcers, external wounds and inflammations. The spermicidal and anti-Trichomonas activity of S. saponaria and its effect on Lactobacillus acidophilus were evaluated. METHODS Water-ethanol (WE) and butanolic (BE) extracts, as well as a purified sample of saponins (SP) from S. saponaria were tested for spermicidal and anti-Trichomona...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 6  issue 3

pages  166- 171

publication date 2019-08

{@ msg @}

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023