Anti fungal activities of fresh garlic extract on candida albicans

Authors

  • Araghizadeh, A.M
  • Fani, M.M Assistant Professor Department of Oral Medicine , School of Dentistry
Abstract:

Introduction: Denture stomatitis is one of the most problem in denture wearers and related to candida albicans. In This study we aimed to determaine garlic extract as an antifungal agent in oral candidiasis. Methods: Candida albicans growth in CHROM Agar was made serial dilution from 16 to 512 mg 1-1 from fresh garlic extract and measured minimmum Inhibitory Concentration. Normal salin was used as control. Results: Garlic extract showed antifungal activities in 32 mg 1-1 concentration, where clotrimazol showed its antifungal activity in 64 mg 1-1 concentration and both Amphoteracin and Nystatin showed their activities in 128 mg 1-1 concentration. Conclusion: Garlic extract in invitro studies is more than Nystatin, Amphoteracin and clotrimazol, eventhough, all of the one effective in higher than 128 mg 1-1 concentration.

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Journal title

volume 13  issue None

pages  143- 148

publication date 2009-10

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