Anti-Diabetic Activity of Terminalia catappa Linn. Leaf Extracts in Alloxan-Induced Diabetic Rats

Authors

  • P Gopkumar
  • R Dhanapal
  • Syed Mansoor Ahmed
  • Vrushabendra Swamy
Abstract:

In view of suggested anti diabetic potential, effect of aqueous and cold extracts of Terminalia Catappa Linn (Combretaceae) leaves, on fasting blood sugar levels and serum biochemical analysis in alloxan-induced diabetic rats was investigated. All the extracts of Terminalia Catappa produced a significant anti diabetic activity at dose levels of 1/5th of their lethal doses. Concurrent histological studies of the pan-creas of these animals showed regeneration by aqueous and cold extracts which were earlier necrosed by alloxan.

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Journal title

volume 4  issue 1

pages  36- 0

publication date 2005-06

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