Analgesic Efficacy of Nephrostomy Tract inFiltration of Bupivacaine and Ketamine after Tubeless Percutaneous Nephrolithotomy: A Prospective Randomized Trial

Authors

Abstract:

Objectives:The aim of the present study was to assess the analgesic efficacy of IV ketamine injection inaddition to nephrostomy tract infiltration of ketamine – bupivacaine on postoperative pain relief after tubeless percutaneous nephrolithotomy (PCNL). Patients and Methods: Patients (n = 100), with renal stone who were candidates for PCNL were randomized to five groups with 20 cases in each: Group C, 10 mL of saline solution was infiltrated into the nephrostomy tract; Group B, 10 ml of 0.25% bupivacaine was infiltrated into the nephrostomy tract; Group BK1, 10 ml of 0.25% bupivacaine plus 0.5mg/kg ketamine was infiltrated into the nephrostomy tract; Group BK2, 10 ml of 0.25% bupivacaine plus 1.5mg/kg ketamine was infiltrated into the nephrostomy tract; Group K, 10 ml of saline solution containing 0.5mg/kg ketamine was intravenously administered. Post-operative pain scores were compared between groups as the primary objective. Comparison of Sedation Scores, rescue analgesic consumption, time to the first rescue analgesics administration, hemodynamic and SpO2 values were regarded as the secondary objective. Results: Mean VAS scores in the first 30 minutes and total analgesic consumption in the first 24 hours of post-operative period were significantly lower in groups BK1 and BK2 in comparison with the other groups (P < 0.05). Also, time to first rescue analgesics administration was longer in the same groups (P < 0.05). Conclusions: Infiltration of ketamine plus bupivacaine provides superior analgesic effects in PCNL surgery compared with other methods.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

analgesic efficacy of nephrostomy tract infiltration of bupivacaine and ketamine after tubeless percutaneous nephrolithotomy: a prospective randomized trial

objectives:the aim of the present study was to assess the analgesic efficacy of iv ketamine injection inaddition to nephrostomy tract infiltration of ketamine – bupivacaine on postoperative pain relief after tubeless percutaneous nephrolithotomy (pcnl). patients and methods: patients (n = 100), with renal stone who were candidates for pcnl were randomized to five groups with 20 cases in each: g...

full text

Use of Surgicel for sealing nephrostomy tract after totally tubeless percutaneous nephrolithotomy.

BACKGROUND AND PURPOSE Fibrin glue and gelatin matrix have been used to seal nephrostomy tracts to reduce bleeding and extravasation after tubeless percutaneous nephrolithotomy (PCNL). In this study, Surgicel (oxidized cellulose) was used to seal the nephrostomy tract after totally tubeless PNL. PATIENTS AND METHODS Twenty patients with kidney calculi were treated with totally tubeless PNL. A...

full text

Safety and efficacy of tubeless percutaneous nephrolithotomy.

OBJECTIVE To determine the safety and efficacy of tubeless percutaneous nephrolithotomy (PCNL). METHODS A quasi-experimental study conducted on 50 patients, at a specialized urology centre. RESULTS The primary success rate of the procedure in terms of stone clearance was 70%. Mean length of hospital stay was 2.44 days. There were no significant complications during or after the surgery. C...

full text

safety and efficacy of tubeless percutaneous nephrolithotomy

percutaneous nephrolithotomy (pnl) is commonly used to treat patients with complex renal calculi. placing a nephrostomy tube is the last step after completing pnl. significant early postoperative discomfort after percutaneous procedure is usually secondary to nephrostomy tubes. the goal of this study is to evaluate the safety of tubeless pnl. a total of 45 patients with mean age of 46.6 years e...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 15  issue 2

pages  619- 626

publication date 2016-06-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023