Active Immunization of Cattle with Killed Vaccines Prepared from Cell Cultured Rinderpest Virus

Active immunization of cattle with killed vaccines prepared from cell-cultured Rinderpest virus.

Cell cultured rinderpest virus inactivated by treatment with 0.01% merthiolate or 0.013% formaldehyde or by exposure to ultraviolet light induced the production of transient neutralizing antibodies in cattle. The addition of aluminium hydroxide or incomplete Freund's adjuvant significantly enhanced neutralizing antibody titres whereas the addition of saponin dramatically depressed the titres. T...

The immunization of cattle against rinderpest in eighteenth-century Europe.

Rinderpest is caused by a morbillivirus closely related to the measles and canine distemper viruses. The pathology and symptomatology of the three diseases are very similar,1 but in terms of mortality, rinderpest is by far the most lethal; in European cattle the death rate often exceeds 80 per cent. The disease was eradicated in Europe over a hundred years ago, but in the eighteenth century an ...

Development of new African horsesickness cell culture killed vaccines

Adjuvants in Immunization with Influenza Virus Vaccines

Subcutaneous inoculation, of PR8 allantoic fluid, or watery suspensions of the virus obtained from allantoic fluid by high-speed centrifugation or by elution after adsorption on red cells induced serum antibodies in experimental animals, which reached the highest levels within 2 weeks after inoculation and were gradually lost thereafter. The addition of killed acid-fast bacteria (Myco. tubercul...

Oral immunization of cattle with hemagglutinin protein of rinderpest virus expressed in transgenic peanut induces specific immune responses.

Rinderpest is an acute, highly contagious often fatal disease of large and small ruminants, both domestic and wild. Global eradication of rinderpest needs a robust, safe and cost-effective vaccine. The causative agent, rinderpest virus (RPV) is an important member of the genus Morbillivirus in the Paramyxoviridae family. We have generated transgenic peanut (Arachis hypogea L.) plants expressing...

Two Rinderpest Live Virus Vaccines, "Lapinized" and "Lapinied-Avianized"

caused by the nature of the parent material and also by leaching in the course of soil formation. f ) Iron. For Japanese paddy soils one percent of active Fe20 l as determined with Mg-ribbon reduction method is critical. Below this value unfavorable effects on the growth of rice may be expected. This threshold value has been adopted for the results of iron determination with a phoco-chemical re...