A Simple, Practical and Efficient Method for the Synthesis of New Disubstituted 1,3,4-oxadiazoles

Authors

  • Ali Ramazani Department of Chemistry, University of Zanjan, Zanjan, Iran
  • Ali Souldozi Department of Chemistry, Urmia Branch, Islamic Azad University, Urmia, Iran
  • Delnia Zamanesazi
  • Pegah Azimzadeh Asiabi Department of Chemistry, University of Zanjan, Zanjan, Iran
  • Sang Woo Joo
  • Yavar Ahmadi North West Reseach Complex, Nuclear Science and Technology Research Institute, Bonab, Iran
Abstract:

Reactions of  N-isocyaniminotriphenylphosphorane with α- chloroketones in the presence ofaromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions toafford new disubstituted 1,3,4-oxadiazole derivatives in high yields.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

nano-rods zno as an efficient catalyst for the synthesis of chromene phosphonates, direct amidation and formylation of amines

چکیده ندارد.

Simple and efficient Heterocyclization method for Synthesis of new pyrimido thiadiazine-3,7-diamine derivatives

New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine  were synthesized via the cyclo condensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate  and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines  in simple a...

full text

Natural kaolin as an efficient recyclable catalyst for the synthesis of new 2,4-disubstituted quinolines

Substituted 2, 4- diphenyl quinolines were synthesized by a multicomponent domino reaction of anilines, aldehydes and terminal aryl alkynes. The synthetic pathway involves the formation of an imine, followed by the intermolecular addition of an alkyne to the imine. This intermediate immediately undergoes ring closure and oxidative aromatization. The reaction is catalyzed by natural kaolin, a st...

full text

Natural kaolin as an efficient recyclable catalyst for the synthesis of new 2,4-disubstituted quinolines

Substituted 2, 4- diphenyl quinolines were synthesized by a multicomponent domino reaction of anilines, aldehydes and terminal aryl alkynes. The synthetic pathway involves the formation of an imine, followed by the intermolecular addition of an alkyne to the imine. This intermediate immediately undergoes ring closure and oxidative aromatization. The reaction is catalyzed by natural kaolin, a st...

full text

Simple and Efficient Method for the Preparation of 5-Bromoisatins

Isatin, N-methyl isatin and N-benzylisatin were smoothly monobrominated in the 5-position by treatment with pyridinium bromochromate (PBC) in acetic acid medium. In the similar conditions indigo underwent bromination and oxidation to give 5-bromoisatin in high yield.

full text

A new and efficient method for the synthesis of 3,4-disubstituted pyrrolidine-2,5-diones.

A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined.

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 11  issue 2

pages  76- 85

publication date 2017-06-01

{@ msg @}

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023