A Case Report of Neonatal Pemphigus vulgaris

Pemphigus vulgaris (PV) is a chronic, rare mucocutaneous autoimmune bullous diseases characterized by flaccid blisters and/or pustules, with secondary erosions of the mucous membranes / skin. Pemphigus vulgaris is threatening patient life by the formation of splits within the epidermis, accompanied by acantholysis (separation of keratinocytes from each other). In this article, a term female neonate with pemphigus vulgaris, born of a 31-year-old mother, was reported. On initial examination by a pediatrician, a number of thin-walled flaccid blisters and burst blisters accompanied with open sores were observed on the skin of hands, feet, face and oral, tongue and throat mucosa. A positive Nikolskychr(chr('39')39chr('39'))s sign confirmed her involvement with the disease.