کیفیت زندگی و عوامل مرتبط با آن در بیماران مبتلا به مولتیپل اسکلروز

Background and Aim: MS is a chronic and destructive inflammatory disease with a not contradiction continuing of life but can influenced the quality of life of patients. The purpose of this study is to determine the quality of life in MS and its related factors. Materials and Methods: This cross-sectional study was performed on 172 patients admitted to the MS Society of Iran (Tehran) and convenience samplings were obtained for 10 months. Tools for data collection were MSQOL-54 and MS patients were also interviewed. Data using descriptive and Analytical tests such as multiple regression were analyzed. Results: The mean age of patients was 34/8 ± 9/6 years. Analysis of 14 sub-domains of quality of life questionnaire showed that the highest average score in the domain of quality of life was social functioning (71/7 ± 21) and the least was role limitations due to physical problems (44/2 ± 39/4). Results of multivariate regression models shown that between age has an significant inverse relationship to domain of physical combined and only variable significant on the combined domain of psychological – psychiatric, Area residential Variable was (p.value 0/001). Conclusions: The study shows that demographic variables medical and economic factors influence the quality of life of patients with multiple sclerosis. Identify the factors related to the quality of life of these patients can be helpful in predicting quality of life. The variables influence on the quality of life for MS patients must be targeted in designing effective intervention programs to improve their quality of life.