پمفیگویید اسکاردهنده چشمی (OCP)
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Abstract:
پمفیگویید غشاهای مخاطی (MMP: Mucous membrane pemphigoid) یک بیماری اتوایمیون سیستمیک تاول‌دهنده است که بیش‌تر پوست و مخاط را درگیر می‌کند. وقتی که یافته‌ها به صورت اولیه و بیش‌تر در ناحیه چشم و ملتحمه باشد، به آن پمفیگویید چشمی اسکاردهنده (OCP: Ocular Cicatricial Pemphigoid) اطلاق می‌شود. این بیماری ناشی از رسوب خطی عوامل ایمنی مانند IgA، IgG، کمپلمان c۳ در ناحیه غشا پایه اپی‌تلیالی است. درگیری چشمی در این بیماری می‌تواند پیشرونده و خطرناک باشد چون حتی منجر به نابینایی می‌شود. در این مطالعه مروری، ما به بررسی بیماری‌زایی، یافته‌های بالینی، درجه‌بندی، تشخیص و روش‌های درمان OCP پرداخته‌ایم.
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Journal title
volume 23 issue 3
pages 209- 220
publication date 2018-06
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