پلئوسیتوزیس استریل مایع نخاع در شیرخواران مبتلا به عفونت ادراری با سن کم‌تر از 3 ماه بستری در بخش کودکان بیمارستان حضرت رسول اکرم(ص) طی سال‌های 1382-1371

During the first 3 months of life, febrile infants are subjected to sepsis workup which includes evaluation for Urinary Tract Infection(UTI) and meningitis. The present study was undertaken to investigate the existence of concomitant meningeal inflammation in infants younger than 90 days affected with UTI. In this retrospective study, 75 out of 249 infants younger than 90 days had positive urine culture(30%). A lumbar puncture was done in 44 infants. 6(10.3%) out of 44 infants with UTI had concomitant urinary and CSF positive culture and Ecoli was the most common urine and CSF pathogen. 28(63.6%)(M: 12, F: 16) out of 44 infants did not have any positive culture for urine and CSF. 10 infants (M: 7, F: 3) had concomitant positive urine culture and sterile pleocytosis in CSF(WBC>=35, >=21, >=15cc/mm3) during the first, second and the third month of life with negative blood culture, respectively. An infant who received oral antibiotic before admission was excluded from the study. On the whole, 20.4% of total 44 infants had concomitant sterile pleocytosis with urinary tract infection. We concluded that sterile meningeal inflammation can follow UTI in neonates and infants at least up to the age of 3 months. Ecoli was the most common urine pathogen associated with aseptic meningitis. This finding suggests that treatment could be directed only to UTI although careful observation of such cases is required until adequate experience is accumulated.