تاثیر تحریک الکتریکی مستقیم فراجمجم های بر اضطراب طی درمان اعتیاد به مواد افیونی از طریق س مزدائی فوق سریع با بیهوشی عمومی

Aims and Background: Opiate addiction, is one of the most prominent health problem in diverse communities which may lead to anxiety during treatment and relapse. This study investigates the efficacy of transcranial direct current stimulation (TDCS) on anxiety during treatment of opiate addiction via the ultra rapid opioid detoxification approach (UROD). Methods and materials: It is a randomized, double blind controlled survey which was conducted on forty scheduled subjects for UROD. TDCS was applied at 24 hour intervals for two sessions by the researcher. The anxiety scores were recorded before the intervention, immediately before UROD, and 24 hours afterwards using Beck questionnaire. Data were analyzed via repeated measure ANOVA using SPSS software. Findings: All the participants were male with mean drug abuse duration of 8.37 ±2.4 and 7.37 ± 2.4 years in intervention and control groups, respectively. According to statistical analysis, anxiety was less in the intervention group and the difference was significant at all time intervals (P-value&le0.008). We observed about 90% decline for anxiety in intervention group one hour after UROD (p-value&le 0.01) while it was about 25%for control group (P-value=0.163) and it increased in the control group within 24 hours. Conclusions: Generally speaking, TDCS is an effective approach to alleviate anxiety due to pre-anesthesia and withdrawal syndromes during UROD.