تابستان 1392

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Dmd058016 1392..1400

Tamoxifen (Tam) is a selective estrogen receptor modulator used to inhibit breast tumor growth. Tam can be directly N-glucuronidated via the tertiary amine group or O-glucuronidated after cytochrome P450–mediated hydroxylation. In this study, the glucuronidation of Tam and its hydroxylated and/or chlorinated derivatives [4-hydroxytamoxifen (4OHTam), toremifene (Tor), and 4-hydroxytoremifene (4O...

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Issn 1392 - 1207

Y. Zuo***, Y. N. Wang*, Y. Zhang**, Z. L. Shen**, Z. S. Chen**, J. Chen**, Q. Y. Xie** *College of Electric and Information Technology, Hunan University, South Lushan Road 1, 410082 Hunan, P. R. China, E-mail: [email protected] **Key Laboratory of Regenerative Energy Electric-Technology of Hunan Province, Changsha University of Science and Technology, Chiling Road 45, 410114 Hunan, P. R. China...

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