بررسی شیوع تریکومونیازیس و تعیین میزان حساسیت دارویی انگل‌های جداشده به مترونیدازول در شهر قروه در سال 1394

Introduction & Objective: Trichomoniasis is one of the most common non viral sexually transmitted diseases caused by Trichomonas vaginalis. The aims of this study were to determine the prevalence of the infection and to consider the metronidazole susceptibility of the T. vaginalis isolates. Materials and Methods: This cross sectional study was conducted on 670 women attending to gynecology clinics in Qorveh, Kurdistan province, in 2015. Diagnosis of trichomoniasis was performed by using Dorset culture medium and wet mount methods. In vitro drug susceptibility testing was done aerobically after establishment of the isolates in axenic culture medium, Diamond.&nbsp; Results: From 670 vaginal samples, eight (1.2%) and four (0.6%) of them were positive for T. vaginalis by wet mount and cultured methods, respectively. Fifty percent of the infected individuals aged from 35 to 44 years old and who were illiterate (P<0.05). Clinical signs and symptoms of trichomoniasis were vaginal discharge, itching, burning sensation, dyspareunia, abdominal pain and greenish discharge. All of the parasites were sensitive to metronidazole with mean of MIC and standard deviation of 1.9 and 0.85&micro;g/ml, respectively.&nbsp;&nbsp; Conclusion: Although, the prevalence of trichomoniasis is relatively low in the studied population but due to the importance of sexually transmitted diseases in public health, strategic measurements are necessary to prevent and control of the infections.&nbsp;&nbsp;