بررسی رشد و تکامل عصبی کودکان با سن بالای 3 سال و سابقه ابتلا به آترزی مری یا فتق دیافراگماتیک مادرزادی

   Background & Aims: Esophageal atresia (EA) is a congenital malformation first described by Durston in 1670 and occurs in 1/2500 births. Congenital diaphragmatic hernia (CDH) is an anatomic anomaly which causes herniation of the abdominal organs into the chest due to incomplete closure of pleuroperitoneal membrane. We preformed this research due to lack of a comprehensive study on growth and neurodevelopment of children with history of congenital esophageal atresia or diaphragmatic hernia. Materials & Methods: This study was conducted on 60 children who underwent surgery for EA (30 patients) or CDH (30 patients) in Tabriz children hospital. Neurological development evaluated with ASQ scoring system and patients’ score in every field recorded and reported according to the national health ministry cut points. Children’s growth was reported according to weight, height, head circumference and BMI. Results: Evaluating patients with EA after 3 years, 17 cases (56.6%) had normal BMI, 9 cases (30%) had BMI less than 5% percentile and 4 cases had BMI above 95% percentile for age. Evaluating their neurological development, four children had abnormal results. Evaluating patients with CDH after 3 years, 16 cases (53%) had normal BMI, 8 cases (26%) had BMI under 5% percentile and 6 (20%) cases had BMI above 95% percentile for age. Also in evaluating neurological development, three children had abnormal results. Conclusion: Overall patients with CDH and EA need intensive care in development, hearing, growth and feeding. Articles mention some of these children with hearing or speech problems had normal neonatal test. More prospective studies are necessary to be conducted.    SOURCE: URMIA MED J 2014: 25(9): 861 ISSN: 1027-3727