بررسی دریافت رژیمی ریز‌مغذی‌ها در چهار فنوتیپ سندرم تخمدان پلی‌کیستیک به تفکیک زیرگروه بر اساس معیار روتردام

Background: Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder with inflammatory and oxidative stress foundation in reproductive-age women in Iran. Some micronutrients have anti-oxidant effects. For the first time, the present study aimed to compare the dietary intake of these anti-oxidant micronutrients in four phenotypes of PCOS. Methods: 182 participants eligible for this five-group comparative study were selected by convenience sampling method. Then they were classified into five groups according to the Rotterdam criteria: A (n=41), B (n=33), C (n=40), D (n=37) and control (without PCOS) (n=31). Dietary intake assessment of zinc, selenium, chromium and carotenoids was carried out by a 168 item Food Frequency Questionnaire. Statistical analysis was performed using SPSS22 software and Kruskal-Wallis (KW) test followed by appropriate post hoc test, Mann-Whitney U (MW). Significant P-value was considered <0.05 for KW test and <0.005 for MW (based on Bonferroni correction). Results: Dietary intakes of zinc and selenium were significantly lower in all phenotypes of PCOS than control group (MW; p<0.005). Chromium intake was significantly lower in phenotype D of PCOS compared to the control group (MW; p<0.001). No significant difference was found between PCOS phenotypes and the control group (KW; p> 0.05). Conclusion: Regarding the research results, it is suggested that modification of the nutritional status of PCOS patients and the increased consumption of these antioxidant micronutrients in the diet will considerably reduce the intensity of PCOS. It will improve the situation of these patients. &nbsp;