بررسی تاثیر درمانی امواج رادیو فرکوئنسی در بیماران با تومورهای متاستاتیک کبد با منشاء پستان

Authors

  • جان بابایی ملا, قاسم دانشیار، گروه هماتولوژی انکولوژی، مرکز تحقیقات سرطان گوارش، دانشگاه علوم پزشکی مازندران، ساری، ایران
  • خادملو, محمد دانشیار، گروه آمار اپیدمیولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران
  • سخایی, یعقوب استادیار، بخش رادیولوژی، دانشکده پزشکی، دانشگاه آزاد واحد ساری، مازندران، ایران
  • طیبی, مریم کارشناس ارشدتصویربرداری پزشکی، بخش رادیولوژی، مرکز آموزشی و درمانی امام خمینی (ره)، دانشگاه علوم پزشکی مازندران، ساری، ایران
  • عقیلی, سید قادر متخصص رادیولوژی، بخش رادیولوژی، مرکز آموزشی و درمانی امام خمینی (ره)، دانشگاه علوم پزشکی مازندران، ساری، ایران
  • مردانشاهی, زهرا استادیار، گروه رادیولوژی، مرکز آموزشی و درمانی امام خمینی (ره)، دانشگاه علوم پزشکی مازندران، ساری، ایران
Abstract:

Background and purpose: Breast cancer is the second leading cause of cancer death in women and the most common cancer causing liver metastases. Radiofrequency ablation (RFA) is a new method in treatment of liver metastases. This study was designed to evaluate the efficacy of RFA on liver metastatic breast tumors. Materials and methods: In a randomized clinical trial, 52 patients with liver metastases from breast cancer who had less than 5 lesions < 5 cm enrolled. They were divided into two groups; an intervention group that received both chemotherapy and RFA and a control group who had only chemotherapy. Different variables were evaluated e.g. changes in lesion size, residual tumor status, and therapy complications. Data was analyzed in SPSS V20. &nbsp; Results: In a randomized clinical trial, 52 patients with liver metastases from breast cancer who had less than 5 lesions < 5 cm enrolled. They were divided into two groups; an intervention group that received both chemotherapy and RFA and a control group who had only chemotherapy. Different variables were evaluated e.g. changes in lesion size, residual tumor status, and therapy complications. Data was analyzed in SPSS V20. &nbsp; Conclusion: RFA was found as a safe and efficient method in treatment of liver metastases from breast carcinoma and showed a significant synergistic effect in patients under ingesting chemotherapy drugs. &nbsp;

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Journal title

volume 27  issue 158

pages  78- 86

publication date 2018-03

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