α-Amylase inhibition and antioxidant activity of Singhnad Guggul in vitro

Authors

  • Ashok Kumar B.S Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka;
  • Gopi Setty Saran Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka;
  • Lokanath V Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka;
  • Naveen Kumar Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka;
  • Saleemulla Khan Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India;
Abstract:

Background & Aim: Singhnad Guggulu is a traditional Ayurvedic formula for detoxifying and rejuvenating the joints. The present study was to investigate the α-amylase inhibition and antioxidant activities of aqueous extract of Singhnad Guggul (AESG). Experimental: α-Amylase inhibition assay by dinitro-salicylic acid method and antioxidant activity by ferric chelating and ferrous reducing assay. Results: AESG indicated that potent α-amylase inhibition activity (IC50= 84.00 µg/ml). AESG also showed ferric chelating and ferrous reducing activities. Recommended applications/industries: Our studies showed that  Singhnad Guggulu possess alpha- amylase and antioxidant properties.

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Journal title

volume 4  issue 2

pages  59- 62

publication date 2013-07-01

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