antidepressant-like effect of aqueous extract from rosa damascena in mice

objective: rosa damascena mill l (r. damascena) is an ornamental plant that has several therapeutic (such as sedative and hypnotic) effects. it also heals depression, grief, nervous stress and tension. in the present study we evaluated antidepressant-like effect of r. damascena using forced swimming test (fst). material and methods: three doses of aqueous extract (15, 60 and 90 mg/kg) was injected intraperitoneally. after 30 min of injection, immobility and swimming times were measured and compared with control (negative control) and imipramine (positive control). results: the results showed that low dose (15mg/kg) of extract significantly increased swimming time and decreased immobility time. however, the two high doses of extract (60 and 90mg/kg) had no significant effect on these parameters.  conclusion: these results proposed antidepressant-like effect of low concentration of aqueous extract of r. damascena.