evaluation of the analgesic effect of thymus kotschyanus hydroalcoholic extract in male mice by formalin and tail flick tests

Authors

vahid nikoui

razi institute for drug research, iran university of medical sciences, tehran, iran sattar ostadhadi

department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran muhammad imran khan

department of pharmacology, school of medicine, international campus, tehran university of medical sciences, tehran, iran. akram allahverdi

department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran azam bakhtiarian

abstract

background and objective: considering the wide side effects of synthetic pain killers, use of herbal drugs in folk medicine as analgesic agents has increased. in the present work, we tried to uncover the pharmacological potential of ethanolic extracts by using various animal models and also to explore the potent antinociceptive effect of the plant thymus kotschyanus. materials and methods: the ethanolic extract from the aerial part of thymus kotschyanus after intraperitoneal administration at doses of 50, 100 and 200 mg/kg was evaluated against pain using formalin test and tail flick test. results: thymus kotschyanus extract at doses of 100 mg/kg (p

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Journal title:
journal of basic and clinical pathophysiology

جلد ۴، شماره ۱، صفحات ۱-۶

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