editorial: the post-exome era

Editorial: The Post-Exome Era

The Iranian Rehabilitation Journal (IRJ) invites research papers on the genetic basis of single gene and complex disorders. This vastly dynamic branch of science will complement the multidisciplinary wealth of expertise in the fields of social welfare and rehabilitation. The past few years have witnessed outstanding research projects on the genetic causes of numerous debilitating disorders, suc...

Editorial—The Last Post

Editorial ? The Last Post Sad news and hard luck stories abound in times of financial stringency and I am sorry to add the plight of the West of England Medical Journal to the list of woes. With the last issue of the journal we asked whether or not recipients would be willing to pay ?20 per annum to receive four quarterly issues of the journal. Unfortunately despite circularising 4,000 doctors ...

Editorial: The Era of the Outcome Measure

T he short history of hearing aid fitting can be divided into three eras . The first era, from roughly 1946 to about 1970, might be described as the era of the PB list. A fitting was successful when the aided speech recognition score for single-syllable words was optimized. The second era, from the 1970s to the present, might be described as the era of the engineering solution . A fitting was s...

Editorial Human epididymis protein 4 : the start of a post - ROMAn era ?

As the result of advances in the understanding of molecular bases of cancer and introduction of targeted therapy, laboratory medicine currently plays an indispensable role in the management of cancer patients (1) . Traditionally, the measurement of tumor markers has been a topic of major interest for both medical oncology and clinical chemistry/laboratory medicine. With time the well-establishe...

Tuberculosis drug discovery in the post-post-genomic era

The expectation that genomics would result in new therapeutic interventions for infectious diseases remains unfulfilled. In the post-genomic era, the decade immediately following the availability of the genome sequence of Mycobacterium tuberculosis, tuberculosis (TB) drug discovery relied heavily on the target-based approach but this proved unsuccessful leading to a return to whole cell screeni...

Editorial: Post-traumatic Stress in the Family