effect of chronic administration of fluoxetine on 6-hydroxydopamine-induced catalepsy in rats
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The effect of chronic administration of buspirone on 6-hydroxydopamine-induced catalepsy in rats.
PURPOSE Several evidences show that serotonergic neurons play a role in the regulation of movements executed by the basal ganglia. Recently we have reported that single dose of buspirone improved 6-hydroxydopamine (6-OHDA) and haloperidol-induced catalepsy. This study is aimed to investigate effect of chronic intraperitoneal (i.p.) administration of buspirone on 6-OHDA-induced catalepsy in male...
full textthe effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولEffect of WR-1065 on 6-hydroxydopamine-induced catalepsy and IL-6 level in rats
Objective(s): Neuroinflammation and oxidative stress play a key role in pathogenesis of Parkinson’s disease (PD). In the present study we investigated the effect of reactive oxygen species (ROS) scavenger WR-1065 on catalepsy and cerebrospinal fluid (CSF) level of interleukin 6(IL-6) and striatum superoxide dismutase (SOD) activity in 6-hydroxydopamine (6-OHDA) induced experimental model of PD...
full textEffect of WR-1065 on 6-hydroxydopamine-induced catalepsy and IL-6 level in rats
OBJECTIVES Neuroinflammation and oxidative stress play a key role in pathogenesis of Parkinson's disease (PD). In the present study we investigated the effect of reactive oxygen species (ROS) scavenger WR-1065 on catalepsy and cerebrospinal fluid (CSF) level of interleukin 6(IL-6) and striatum superoxide dismutase (SOD) activity in 6-hydroxydopamine (6-OHDA) induced experimental model of PD. ...
full texteffect of wr-1065 on 6-hydroxydopamine-induced catalepsy and il-6 level in rats
objective(s): neuroinflammation and oxidative stress play a key role in pathogenesis of parkinson’s disease (pd). in the present study we investigated the effect of reactive oxygen species (ros) scavenger wr-1065 on catalepsy and cerebrospinal fluid (csf) level of interleukin 6(il-6) and striatum superoxide dismutase (sod) activity in 6-hydroxydopamine (6-ohda) induced experimental model of pd...
full textBuspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats.
Receptors for 5-HT(1A) are widely distributed throughout the basal ganglia, and their activation results in an inhibition of dopamine (DA) release. This study aimed to investigate the effect of buspirone, as a partial agonist of 5-HT(1A) receptors, on 6-hydroxydopamine (6-OHDA)-induced catalepsy in male Wistar rats. Catalepsy was induced by unilateral infusion of 6-OH-DA (6 microg/2 microl/rat)...
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research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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