evaluation of anti-arthritic and anti-inflammatory activity of sudard, a poly herbal formulation
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abstract
rheumatoid arthritis is a chronic multi-system disease of unknown cause. it affects the people in their prime of life, predominantly between the ages of 20-50 years with unpredictable course. sudard is used in the ayurvedic system of medicine for the treatment of inflammation and pain associated with rheumatoid arthritis, osteo-arthritis, frozen shoulder, sciatica, ankylosing spondylitis and chronic backache. our study was aimed to evaluate efficacy of sudard using different animal models such as formalin (2% v/v) induced acute inflammation, carrageen (1% v/v) induced polyarthritis, adjuvant induced arthritis, subacute inflammation by sponge implantation technique and analgesic activity by eddy’s hot plate method. the results indicate that the formulation sudard possesses anti-inflammatory, anti-arthritic and analgesic activities in the experimental animal models.
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Journal title:
iranian journal of pharmacology and therapeuticsجلد ۶، شماره ۱، صفحات ۷۱-۰
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