effects of turnera ulmifolia (linn.) leaves on blood glucose level in normal and alloxan-induced diabetic rats

Authors

d. prabu

m. nappinnai

k. ponnudurai

a. thirugnanasambanthan

abstract

the methanolic extract of leaves of turnera ulmifolia l was evaluated for its effect on blood glucose in alloxan-induced diabetic and euglycemic rats. the extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. glibenclamide (10 mg/kg, p.o.) was used as standard for control group. in euglycemic rat, extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. extract at 400 mg/kg and glibenclamide significantly reduced blood glucose level in normal and alloxan-induced diabetic rats and raised the liver glycogen content significantly. this indicates that the leaves extract of turnera ulmifolia l posses anti-hyperglycemic activity.

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Journal title:
iranian journal of pharmacology and therapeutics

جلد ۸، شماره ۲، صفحات ۷۷-۰

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