morphological properties of different measles virus vaccine strains
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Edmonston Vaccine Lineage Sequences of Measles Virus Strains in the Comparison of Predicted Amino Acid
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Differential type I IFN-inducing abilities of wild-type versus vaccine strains of measles virus.
Laboratory adapted and vaccine strains of measles virus (MV) induced type I IFN in infected cells. The wild-type strains in contrast induced it to a far lesser extent. We have investigated the mechanism for this differential type I IFN induction in monocyte-derived dendritic cells infected with representative MV strains. Laboratory adapted strains Nagahata and Edmonston infected monocyte-derive...
full text[Susceptibility of Vero cell line to vaccine strains of the measles virus].
Vero cells used by distinct measles vaccine control laboratories had their susceptibility to Moraten, Schwarz and Biken CAM-70 vaccine strains assayed. Of a total of 72 lots of measles vaccine whose potency was titrated by microtechnique in two Vero cell samples (Vero IB and Vero INCQS), 25 had been produced with Moraten strain, 24 with Schwarz and 23 with Biken CAM-70. The statistical analysis...
full textAnalysis of the noncoding regions of measles virus strains in the Edmonston vaccine lineage.
The noncoding sequence of five Edmonston vaccine viruses (AIK-C, Moraten, Rubeovax, Schwarz, and Zagreb) and those of a low-passage Edmonston wild-type (wt) measles virus have been determined and compared. Twenty-one nucleotide positions were identified at which Edmonston wt and one or more vaccine strains differed. The location of some of these nucleotide substitutions suggests that they may i...
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archives of razi instituteجلد ۳۳، شماره ۱، صفحات ۱۳-۲۲
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