safety, effectiveness and economic evaluation of intra-operative radiation therapy: a systematic review
Authors
abstract
background: intra-operative radiation therapy (iort) is the transfer of a single large radiation dose to the tumor bed during surgery with the final goal of improving regional tumor control. this study aimed to investigate the safety, effectiveness and economic evaluation of intra-operative radiation therapy. methods : the scientific literature was searched in the main biomedical databases (centre for reviews and dissemination, cochrane library and pubmed) up to march 2014. two independent reviewers selected the papers based on pre-established inclusion criteria, with any disagreements being resolved by consensus. data were then extracted and summarized in a structured form. results from studies were analyzed and discussed within a descriptive synthesis. results : sixteen studies met the inclusion criteria. it seems that outcomes from using intra-operative radiation therapy can be considered in various kinds of cancers like breast, pancreatic and colorectal cancers. the application of this method may provide significant survival increase only for colorectal cancer, but this increase was not significant for other types of cancer. this technology had low complications and it is relatively safe. using intra-operative radiation therapy could potentially be accounted as a cost-effective strategy for controlling and managing breast cancer. conclusion : according to the existing evidences, that are the highest medical evidences for using intra-operative radiation therapy, one can generally conclude that intra-operative radiation therapy is considered as a relatively safe and cost-effective method for managing early-stage breast cancer and it can significantly increase the survival of patients with colorectal cancer. also, the results of this study have policy implications with respect to the reimbursement of this technology.
similar resources
Safety, effectiveness and economic evaluation of intra-operative radiation therapy: a systematic review
Background: Intra-operative radiation therapy (IORT) is the transfer of a single large radiation dose to the tumor bed during surgery with the final goal of improving regional tumor control. This study aimed to investigate the safety, effectiveness and economic evaluation of intra-operative radiation therapy. Methods : The scientific literature was searched in the main biomedical databases ...
full textSafety, effectiveness and economic evaluation of intra-operative radiation therapy: a systematic review
BACKGROUND Intra-operative radiation therapy (IORT) is the transfer of a single large radiation dose to the tumor bed during surgery with the final goal of improving regional tumor control. This study aimed to investigate the safety, effectiveness and economic evaluation of intra-operative radiation therapy. METHODS The scientific literature was searched in the main biomedical databases (Cent...
full textThe safety and effectiveness of different methods of earwax removal: a systematic review and economic evaluation.
BACKGROUND Build-up of earwax is a common reason for attendance in primary care. Current practice for earwax removal generally involves the use of a softening agent, followed by irrigation of the ear if required. However, the safety and benefits of the different methods of removal are not known for certain. OBJECTIVES To conduct evidence synthesis of the clinical effectiveness and cost-effect...
full textThe effectiveness and safety of Iranian herbal medicines for treatment of premenstrual syndrome: A systematic review
Objective: Premenstrual syndrome (PMS) is one of the most common problems among women of reproductive age. The popularity of complementary/alternative therapies has grown in recent years, and these treatments have been more commonly used by women (48.9%) than men (37.8%). The aim of this systematic review was to assess effectiveness and safety of Iranian herbal medicines for treatment of premen...
full textClinical effectiveness and cost-effectiveness of growth hormone in children: a systematic review and economic evaluation.
full text
The clinical effectiveness and cost-effectiveness of exercise referral schemes: a systematic review and economic evaluation.
BACKGROUND Exercise referral schemes (ERS) aim to identify inactive adults in the primary-care setting. The GP or health-care professional then refers the patient to a third-party service, with this service taking responsibility for prescribing and monitoring an exercise programme tailored to the needs of the individual. OBJECTIVE To assess the clinical effectiveness and cost-effectiveness of...
full textMy Resources
Save resource for easier access later
Journal title:
medical journal of islamic republic of iranجلد ۲۹، شماره ۱، صفحات ۷۸۴-۷۹۳
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023