new insight into the application of outer membrane vesicles of gram-negative bacteria
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abstract
this review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (omvs), originating from the surface of gram negative bacteria including their outer membrane proteins and lipopolysaccharides. moreover, the functional roles and applications of omvs in medical research such as omv-based vaccines, omv adjuvants properties, omv carriers in conjugated vaccines as well as in drug vehicles and delivery systems are discussed. finally, new applications of these macromolecules as biotechnological tools are briefly presented.
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New insight into the application of outer membrane vesicles of Gram-negative bacteria
This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV ...
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Conditions that impair protein folding in the Gram-negative bacterial envelope cause stress. The destabilizing effects of stress in this compartment are recognized and countered by a number of signal transduction mechanisms. Data presented here reveal another facet of the complex bacterial stress response, release of outer membrane vesicles. Native vesicles are composed of outer membrane and pe...
full textOuter Membrane Vesicles (OMVs) of Gram-negative Bacteria: A Perspective Update
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Journal title:
vaccine researchجلد ۲، شماره ۵، صفحات ۹۳-۹۶
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