Biodetector Using Acoustic Devices : Comparison between Love Waves and Qcm
نویسندگان
چکیده
The first applications of acoustic devices to chemical detection were proposed by Sauerbray in 1959 [1]. For application in liquid media, mainly quartz microbalance (QCM) sensors have been investigated. Recent works on Love waves devices for gas detection have demonstrated definitely their superiority, in particular in term of mass loading effect sensitivity [2]. As the shear horizontal polarization allows working with an adjacent liquid, three years ago, we decided to demonstrate similar potentialities for biochemical detection. An interdisciplinary and successful collaboration between immunologists and electronics researchers allowed realtime detection based on an immunological model with a Love wave device [3]. In quite the same time, a German team has led similar works with the same immunological species on QCM devices [4]. They used very sensitive QCM devices, obtained by locally thinning quartz crystals, which allows to realize high fundamental frequency (HFF) QCM.
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