LPIN2 gene mutation in a patient with overlapping neutrophilic disease (pyoderma gangrenosum and aseptic abscess syndrome)
نویسندگان
چکیده
PG: pyoderma gangrenosum N eutrophilic disease encompasses a spectrum of conditions characterized by neutrophilic aseptic inflammation in the skin and internal organs. The prototype of this group is pyoderma gangrenosum (PG); however, the existence of transitional and overlap forms is always a consideration when facing patients with autoinflammation. We report on a patient with overlapping neutrophilic disease with a novel mutation in a gene involved in autoinflammation.
منابع مشابه
Treatment of a refractory case of pyoderma gangrenosum with cyclosporine and mycophenolate mofetil
Pyoderma gangrenosum is a rare non infectious neutrophilic dermatosis commonly associated with underlying systemic disease. Many treatment regimens have been reported. Herein, we report a case of refractory pyoderma gangrenosum with good response to combination of cyclosporine and mycophenolate mofetil.
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