Insulin studies in temporary neonatal hyperglycaemia.
نویسنده
چکیده
Hoyt, R. E., Morrison, L. M., and Levine, M. G. (1961). The nature of the hemagglutinating agent noted in the blood serum of patients with viral hepatitis. journal of Laboratory and Clinical Medicine, 58, 104. Morrison, L. M., and Hoyt, R. E. (1957). Hemagglutination reactions noted in viral hepatitis. journal of Laboratory and Clinical Medicine, 49, 774. Morrison, L. M., Hoyt, R. E., Levine, M., Rosenthal, M., Holeman, R. L., and Stevens, M. R. (1960). Further experience with hemagglutination in viral hepatitis. American journal of Gastroenterology, 33, 461. Morrison, L. M., Rosenthal, M., Holeman, R., and Stevens, M. (1961). The relationship of viral hepatitis to cirrhosis of the liver. American Journal of Gastroenterology, 35, 371. Rubin, B. A., Kemp, H. A., and Bennett, H. D. (1957). Mechanism of agglutination of Macaca rhesus erythrocytes by human hepatitis serum. Science, 126, 1117. Stokes, J. F., Jr., Wolman, I. J., Blanchard, M. C., and Farquhar, J. D., (1951). Viral hepatitis in the newborn: clinical features, epidemiology, and pathology. (Abstr.) American journal of Diseases of Children, 82, 213.
منابع مشابه
Neonatal hyperglycaemia: case report with plasma insulin studies.
It is now established that the dysmature infant, of low birthweight for the period of gestation, may develop a diabetic state in the neonatal period (Arey, 1953; Engleson and Zetterqvist, 1957; Hutchison, Keay, and Kerr, 1962). This condition, which is temporary and has a good prognosis, has to be distinguished from other causes of hyperglycaemia. Permanent diabetes mellitus occurs rarely in th...
متن کاملHypoglycaemia and temporary hyperglycaemia in infants of low birth weight for materity.
The importance of hypoglycaemia in newborn infants who have suffered intrauterine malnutrition is now well established (Neligan, 1965). The number of reports on this subject is not yet extensive (Cornblath, Odell, and Levin, 1959; Brown and Wallis, 1963a; Neligan, Robson, and Watson, 1963; Tynan and Haas, 1963; Neligan, 1965), and gives the impression that the ultimate prognosis is often good, ...
متن کاملHyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells
Insulin secretion from pancreatic β-cells is impaired in all forms of diabetes. The resultant hyperglycaemia has deleterious effects on many tissues, including β-cells. Here we show that chronic hyperglycaemia impairs glucose metabolism and alters expression of metabolic genes in pancreatic islets. In a mouse model of human neonatal diabetes, hyperglycaemia results in marked glycogen accumulati...
متن کاملNeonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report
Neonatal diabetes mellitus (DM) develops within the first six weeks of life with basic findings including dehydration, hyperglycaemia, and mild or no ketonemia/ketonuria. It can be either transient or permanent. Here, we report a case of a one-month-old infant with permanent neonatal diabetes, due to pancreatic hypoplasia, accompanied by diabetic ketoacidosis (DKA). The hyperglycaemia and ketoa...
متن کاملComputer-determined dosage of insulin in the management of neonatal hyperglycaemia (HINT2): protocol of a randomised controlled trial
INTRODUCTION Neonatal hyperglycaemia is frequently treated with insulin, which may increase the risk of hypoglycaemia. Computer-determined dosage of insulin (CDD) with the STAR-GRYPHON program uses a computer model to predict an effective dose of insulin to treat hyperglycaemia while minimising the risk of hypoglycaemia. However, CDD models can require more frequent blood glucose testing than c...
متن کاملEffective glycaemic control critically determines insulin cardioprotection against ischaemia/reperfusion injury in anaesthetized dogs.
AIMS Experimental evidence has shown significant cardioprotective effects of insulin, whereas clinical trials produced mixed results without valid explanations. This study was designed to examine the effect of hyperglycaemia on insulin cardioprotective action in a preclinical large animal model of myocardial ischaemia/reperfusion (MI/R). METHODS AND RESULTS Anaesthetized dogs were subjected t...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 46 247 شماره
صفحات -
تاریخ انتشار 1971