Experimental study of multiple-intermittent cryogen spurts and laser pulses for the treatment of port wine stain birthmarks
نویسندگان
چکیده
Cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during pulsed laser treatment of port wine stain (PWS) birthmarks. Unfortunately, the current approach to CSC does not provide the necessary epidermal protection for all patients, particularly those with darker skin types. Therefore, alternative approaches need to be sought to improve PWS laser therapy. On a previous numerical study we showed that using multiple-intermittent CSC spurts and laser pulses could permit, under certain conditions, the use of higher laser doses while providing sufficient epidermal protection. In this study we show some results of ongoing experimental to study the feasibility of implementing clinically such an approach.
منابع مشابه
Cryogen spray cooling efficiency: improvement of port wine stain laser therapy through multiple-intermittent cryogen spurts and laser pulses.
BACKGROUND AND OBJECTIVES Cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser treatment of port wine stain (PWS) birthmarks. Unfortunately, CSC may not provide the necessary protection for patients with high concentrations of epidermal melanin. The objectives of this study are to: (1) provide a definition of cooling efficiency (eta) based on the amount of h...
متن کاملIntermittent cryogen spray cooling for optimal heat extraction during dermatologic laser treatment.
Fast heat extraction is critically important to obtain the maximal benefit of cryogen spray cooling (CSC) during laser therapy of shallow skin lesions, such as port wine stain birthmarks. However, a film of liquid cryogen can build up on the skin surface, impairing heat transfer due to the relatively low thermal conductivity and higher temperature of the film as compared to the impinging spray ...
متن کاملThermal Interaction of Cryogen Spray with Human Skin under Hypobaric Pressures
Clinical results of port wine stain (PWS) birthmarks laser therapy have shown that dark purple lesions usually respond well to the first 3–5 treatments. However, for most PWS, complete blanching is never achieved, and the lesion stabilizes at a red-pink color. We have recently demonstrated that with the aid of a local vacuum applied to the lesion site prior to laser irradiation, photocoagulatio...
متن کاملHeat Transfer Dynamics during Treatment of Port Wine Stain Birthmarks with Multiple-intermittent Cryogen Spurts and Laser Pulses
Port wine stain (PWS) is a congenital, progressive vascular malformation of human skin. Presently, all PWS patients are treated using single cryogen spurt and single laser pulse exposure (SCS-SLP), which does not produce complete lesion blanching in the vast majority of patients. In this study, the feasibility of applying multiple cryogen spurts intermittently with multiple laser pulse exposure...
متن کاملEffect of skin indentation on heat transfer during cryogen spray cooling.
BACKGROUND AND OBJECTIVES Cryogen spray cooling (CSC) is used to pre-cool the epidermis during dermatological laser procedures such as treatment of port wine stain (PWS) birthmarks, hair removal, and non-ablative photorejuvenation. Thus far, heat transfer studies related to CSC optimization have assumed a flat surface but clinical observation suggests that human skin indents due to the force of...
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