Transgenerational Epigenetics: Current Controversies and Debates
نویسندگان
چکیده
Chapter Outline Introduction 371 Epigenetics and Behavioral Biology 374 Epigenotypes Versus Epiphenotypes (Molecular vs. Molar Epigenetics) 375 The Epigenotype or Molecular Epigenetics 375 The Epiphenotype or Molar Epigenetics 376 Context-Dependent vs. Germline-Dependent Epigenetic Modifications 376 Context-Dependent Epigenetic Modification 377 Germline-Dependent Epigenetic Modification 378 Transgenerational Inheritance 378 Body Burdens Include Our Personal Exposures, and Those Inherited from Our Ancestors 380 The Fallacy of Ecologically Relevant Dosages 381 Experimental Simulation of Exposures in the Real World (Mixtures and Synergy) 382 Thresholds 383 Species, Sex, and Individual Differences 384 Species Differences in Hormone Abundance, Metabolism, and Receptor–Ligand Interactions 384 Sex Differences in Responses 385 Individual Differences 386 Conclusion 386 Glossary 387 References 387
منابع مشابه
Chapter 26 – Transgenerational Epigenetics: Current Controversies and Debates
Chapter Outline Introduction 371 Epigenetics and Behavioral Biology 374 Epigenotypes Versus Epiphenotypes (Molecular vs. Molar Epigenetics) 375 The Epigenotype or Molecular Epigenetics 375 The Epiphenotype or Molar Epigenetics 376 Context-Dependent vs. Germline-Dependent Epigenetic Modifications 376 Context-Dependent Epigenetic Modification 377 Germline-Dependent Epigenetic Modification 378 Tra...
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