Delta Dental Plans Association National Science Advisory Committee Report
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چکیده
Xylitol has most commonly been studied in chewing gum, with just a few studies looking at its action in toothpaste, mouthrinse, or tablets. Most of the studies have been done in children, with fewer studies in adults. Very little has been done to look at effects of xylitol in patients over 65 or root surfaces (Makinen, et.al 1995b). There is an abundance of available evidence on xylitol’s action in caries, so conclusions can be reached with confidence. There is strong evidence that xylitol, in sufficiently high dosage (5-10 g/day), consistent and prolonged use, and with three or more exposures per day, reduces the incidence of caries. Classifying the evidence as strong, moderate, or weak, there is strong evidence that the consistent use of xylitol reduces interdental acid production, and strong evidence that it reduces bacterial counts of the mutans streptococci. There is also moderate evidence that xylitol promotes enamel remineralization, though only weak evidence that it reduces plaque accumulation.
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