Adaptive Control of an Optical Trap for Single Molecule and Motor Protein Research

نویسنده

  • Kurt Daniel Wulff
چکیده

Engineering—Mechanical) ADAPTIVE CONTROL OF AN OPTICAL TRAP FOR SINGLE MOLECULE AND MOTOR PROTEIN RESEARCH by

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Sensorless Indirect Field Oriented Control of Single-sided Linear Induction Motor With a Novel Sliding Mode MRAS Speed Estimator

This paper proposes a new sliding mode control (SMC)  based model reference adaptive system (MRAS) for sensorless indirect field oriented control (IFOC) of a single-sided linear induction motor (SLIM). The operation of MRAS speed estimators dramatically depends on adaptation mechanism. Fixed-gain PI controller is conventionally used for this purpose which may fail to estimate the speed correctl...

متن کامل

Bidirectional transport by molecular motors: Enhanced processivity and response to external forces (Supporting material)

Our theory is based on single motor properties as briefly summarized in Section 2 of the main text, and described in more detail here. Each motor binds to the filament, walks along it, and unbinds from it stochastically with force-dependent rates derived from single molecule experiments. In these experiments, the motor moves against a load force F exerted by an optical trap. Unbinding rate. The...

متن کامل

Mechanical properties of single motor molecules studied by three-dimensional thermal force probing in optical tweezers.

A new method combining three-dimensional (3D) force measurements in an optical trap with the analysis of thermally induced (Brownian) position fluctuations of a trapped probe was used to investigate the mechanical properties of a single molecule, the molecular motor kinesin. One kinesin molecule attached to the probe was bound in a rigorlike state to one microtubule. The optical trap was kept w...

متن کامل

An automated two-dimensional optical force clamp for single molecule studies.

We constructed a next-generation optical trapping instrument to study the motility of single motor proteins, such as kinesin moving along a microtubule. The instrument can be operated as a two-dimensional force clamp, applying loads of fixed magnitude and direction to motor-coated microscopic beads moving in vitro. Flexibility and automation in experimental design are achieved by computer contr...

متن کامل

An Adaptive Nonlinear Controller for Speed Sensorless PMSM Taking the Iron Loss Resistance into Account (RESEARCH NOTE)

In this paper, an adaptive nonlinear controller is designed for rotor Surface Permanent Magnet Synchronous Motor (SPMSM) drive on the basis of Input-Output Feedback Control (IOFC), and Recursive Least Square (RLS) method. The RLS estimator detects the motor electromechanical parameters, including the motor iron loss resistance online. Moreover, a Sliding-Mode (SM) observer is developed for onli...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2007