A Censored Multinomial Regression Model for Perinatal Mother to Child Transmission of HIV
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چکیده
منابع مشابه
A coarsened multinomial regression model for perinatal mother to child transmission of HIV
BACKGROUND In trials designed to estimate rates of perinatal mother to child transmission of HIV, HIV assays are scheduled at multiple points in time. Still, infection status for some infants at some time points may be unknown, particularly when interim analyses are conducted. METHODS Logistic regression models are commonly used to estimate covariate-adjusted transmission rates, but their met...
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In Iran 8% of HIV- infected cases are women. Since most of them are young and in childbearing ages, in case of becoming pregnant and not receiving preventive measures, they can infect their child. Without Preventive measures transmission rate is 15 to 45 percent. Several factors such as sever stage of HIV and AIDS ,CD4 low count, high viral loud, acute retroviral phase, STDs, vaginal delivery, ...
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HLA class II antigens are central in initiating antigen-specific CD4+ T cell responses to HIV-1. Specific alleles have been associated with differential responses to HIV-1 infection and disease among adults. This study aims to determine the influence of HLA class II genes and their interactive effect on mother-child perinatal transmission in a drug naïve, Mother-Child HIV transmission cohort es...
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In 2009, the US Centers for Disease Control and Prevention (CDC) estimated that almost 11,000 children younger than 13 years old in the United States were diagnosed with HIV infection. Of those, it is estimated that the vast majority (88%) acquired the HIV infection perinatally. Given that both perinatal transmission is the most common route of HIV infection in children under 13 in the US and t...
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BACKGROUND HLA-G gene is a non-classical MHC class 1 molecule that is highly expressed in the trophoblast at the maternal-fetal interface. In an attempt to elucidate possible immunological mechanisms facilitating protection of infants born to human immunodeficiency virus type (HIV-1) infected mothers, we have been studying genetic variations in the coding and untranslated regions of HLA-G antig...
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